The Evidence
Blueprint

BEHAVIORAL HEALTH

Research-Grade

Real-world data

Building the future of behavioral health with real-world data and analytics
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the urgent need

Behavioral health disorders are a defining problem of our generation.

Behavioral health is a fundamental and persistently overlooked aspect of overall health. Mental and substance use disorders impact a staggering 970 million people worldwide, with over US $1 trillion in global economic burden each year. Despite the skyrocketing crisis, progress has lagged behind other disease areas. Less than half of those living with major depression, the most widespread mental illness, reach remission on currently available treatments. Recent rising awareness has driven demand in a system unequipped to support the depth and breadth of need.

There is a debilitating evidence gap that inhibits research and innovation, stemming from inherent limitations in behavioral health: complex disease etiologies, lack of quantifiable biomarkers, and institutional silos. Despite decades of research, we still do not know how to alleviate most behavioral health disorders.

We need new solutions, and we need them now.

Code Templates

Analytics Tools

Research-Grade EHR

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THE BLUEPRINT

Reimagining Behavioral Health

NeuroBlu is a data and analytics platform that enables uniquely powerful evidence generation. With the most robust behavioral health database of its kind and seamless AI-powered analytic tools, NeuroBlu gives researchers, life sciences companies, clinicians, and other industry partners the ability to generate insights like never before.

More than just an analytics platform, NeuroBlu enables discovery to improve lives.

Behavioral health transformation starts here.

Insights

Scientifically Validated,
Clinically Meaningful Insights

NeuroBlu gives users unprecedented ability to generate novel insights, with longitudinal structured data on disease severity, symptoms, side effects, medications, and external stressors.

Abstract representation of a non-linear research approach

Explore

Delve into a rich, unique database with an easy-to-use interface designed for fast and scalable queries.

Analyze

Investigate research questions and enhance care delivery with state-of-the-art analytics tools, including our proprietary NLP and AI/ML algorithms which seamlessly integrates into our solutions.

Discover

Generate insights with longitudinal severity scores and NLP-derived signs and symptoms, external stressors, and side effects.

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DATA

Powerful Behavioral Health Data

NeuroBlu is fueled by a uniquely powerful behavioral health database, the only one of its kind.

Leading Source for Behavioral Health Real-World Evidence

250,000,000+

rows of data

1,000,000+

patients

20+

years of longitudinal data

75,000,000+

clinical encounters

30+

geographically-
diverse psychiatry sites

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Comprehensive

Over 20 years of longitudinal data and patient records spanning both inpatient and outpatient sites including hospitals, emergency departments, and community psychiatry clinics.

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Rich

Meaningful clinical information not typically captured in a structured way is transformed into analyzable keywords representing a large family of symptoms, side effects, and external stressors.

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Outcomes

Quantitative outcome measures allow users to track patient function and outcomes over time and understand the effectiveness of different interventions.

Behavioral Health Conditions

For example:

Substance use disorders

255,000+ patients

Major depressive disorder

251,000+ patients

Bipolar disorder

134,000+ patients

Attention-deficit/hyperactivity disorder

82,000+ patients

Post-traumatic stress disorder

63,000+ patients

Schizoaffective disorder

34,000+ patients

Schizophrenia

33,000+ patients

Borderline personality disorder

19,000+ patients

Autism spectrum disorder

16,000+ patients

Substance use disorders
255,000+ patients

Major depressive disorder:
251,000+ patients

Bipolar disorder
134,000+ patients

Attention-deficit/hyperactivity disorder
82,000+ patients

Post-traumatic stress disorder
63,000+ patients

Schizoaffective disorder
34,000+ patients

Schizophrenia
33,000+ patients

Borderline personality disorder
19,000+ patients

Autism spectrum disorder
16,000+ patients

Behavioral Health Assessments

For example:

Brief Bipolar Disorder Symptom Scale (BDSS)

Brief Negative Symptom Assessment (BNSA)

Clinical Global Impressions (CGI-I/CGI-S)

Columbia-Suicide Severity Rating Scale (C-SSRS)

Global Assessment of Functioning (GAF)

Patient Health Questionnaire-9 (PHQ-9)

Positive Symptom Rating Scale (PSRS)

The Daily Living Activities–20 (DLA-20)

The Quick Inventory of Depressive Symptomatology (QIDS)

Pharmacological Treatments

For example:

Antidepressants

Antipsychotics

Anxiolytics

Hypnotics and sedatives

Mood stabilizers

Psycholeptics

Psychostimulants

ENRICHMENT

Uncovering Real-World
Insights with NLP

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Over 300 psychiatry-specific labels

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NLP model trained on notes from over 11,000 clinicians and 6 million data points

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Disease severity score for most encounters

Our novel Natural Language Processing (NLP) algorithm transforms rich clinician notes into structured data that predicts disease severity.

Clinician notes are valuable troves of information on patient experience, treatment response, and outcomes that are not captured in other EHR or claims data sources. Analyzing unstructured notes is typically arduous and time-consuming.

Our proprietary NLP model unlocks insights from clinician notes, allowing for large-scale analysis and disease modeling. We have over 300 psychiatry-specific structured labels on granular symptoms, side effects, external stressors, and more. These labels can also be used to predict disease severity based on CGI-S scores, opening up a new frontier for scalable analysis of patient experiences through clinician notes.

Going beyond standard context-aware keyword search NLP approaches, our proprietary NLP models are designed specifically to handle the complexity of psychiatric care, which lacks standardized terminology and relies heavily on subjective assessments and verbose descriptions. Our NLP approach leverages the latest innovation in machine learning and language modeling to interpret full sentences using an attention based deep learning, producing granular structured data labels.

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Over 300 psychiatry-specific labels

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NLP model trained on notes from over 11,000 clinicians and 6 million data points

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Disease severity score for every encounter

Features

Accelerate Evidence Generation with Fast, Scalable Studies

Designed by a team of scientists, clinicians, and industry experts, NeuroBlu's robust tools drive Real-World Evidence generation with unparalleled ease.

NeuroBlu's custom-built architecture brings the power of high-performance computing and innovation to real-world studies. User-friendly tools streamline typically laborious and error-prone analysis steps, enabling users to get to insights without having to spend hours cleaning data and troubleshooting code. Built-in custom libraries let you use the data with ease - no need to spend hours navigating a complex data model, because our data scientists did it for you.

Data Explorer showcasing multiple number of data tables available,

View data and get high-level summaries of the dataset, including a set of visualizations describing the population characteristics

Cohort Builder interface with updated statistics based on the user's cohort selection.

Intuitive graphical interface allowing you to build your study cohort using a few clicks, and view cohort characteristics with charts updated in real-time

Category Mapper that shows antidepressant drugs selected.

Simple and streamlined tool to build groupings of values (e.g., diagnosis codes or drug type) to create custom categories for use across multiple projects in a simple and less error-prone way

R Code interface that showcases the code panel with different types of files such as 'R', CSV, Image.

Perform custom analytics in R with your own code or from our built-in library of code templates for popular studies

OTHERS

BluSuite

PRO

Perform powerful analyses using Holmusk's proprietary advanced analytics packages, created by our data scientists to provide easy access to frequently used analytics methods such as survival analysis and comparative effectiveness studies

Project Notes

Seamlessly annotate, replicate, and compare results across your research studies with our integrated Project Notes feature, allowing users to write and store research notes

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Value

Bring Treatments to Market Faster with Real-World Evidence

Powerful insights to drive clinical and commercial success in life sciences, and improve care delivery.

Research and Development

Support clinical development and increase success of trial designs.

R&D Strategy

  • Identify patient subsegments with unmet needs, such as opioid use disorder patient with poor outcomes despite being on a treatment regimen.

Clinical Development

  • Significantly accelerate clinical trial recruitment by screening patient characteristics efficiently. For instance, easily identify characteristics of patients with Major Depressive Disorder who display symptoms of anhedonia.
  • Understand characteristics associated with varying levels of severity in patients with Major Depressive Disorder, in order to create patient subsegments to inform trial design for compounds targeting treatment-resistant depression.

Medical Affairs

Derive patient specific insights and population level trends in behavioral health using AI/ML algorithms on large sets of real-world behavioral health data.

  • Compare key endpoints — such as Clinical Global Impression-Severity (CGI-S), Global Assessment of Function (GAF), and side effect burden — for patients on competitor drugs to provide evidence of differentiated benefit.
  • Assess patient-centric endpoints — such as mood, function, and engagement — that can significantly impact outcomes in real-world settings, including treatment adherence, clinician prescription decisions, and overall patient health.
  • Evaluate prescription patterns of off-label drugs for Major Depressive Disorder to identify related behavioral health indications for further clinical evaluation.
  • Guide evidence-driven care to enhance care management for patients at risk and to improve behavioral health outcomes.
  • Produce publications highlighting therapeutic benefit in real-world settings to increase impact factor with key opinion leaders and other health care professionals.

Market Access and HEOR

Evaluate comparative effectiveness of pharmacological treatments in the real world and enable value-based care.

  • Establish cost-benefit by determining comparative effectiveness of treatments beyond standard clinical endpoints, such as hospitalization among patients on different drug formulations (e.g. oral versus long-acting injectable atypical antipsychotics).
  • Measure drug performance in real-world settings and identify opportunities for value-based strategies.
EXPLORE USE CASES
Testimonials

What our customers are saying

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Jane Doe

Job Role
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I have people in my family with certain conditions, and with this collaboration we can perhaps change the way behavioral health is treated in the long-term.

Jane Doe

Job Role
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I have people in my family with certain conditions, and with this collaboration we can perhaps change the way behavioral health is treated in the long-term.

Jane Doe

Job Role
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I have people in my family with certain conditions, and with this collaboration we can perhaps change the way behavioral health is treated in the long-term.

Jane Doe

Job Role
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SOLUTIONS

NeuroBlu Solutions

NeuroBlu platform seamlessly connects our behavioral health data and analytics capabilities with our behavioral health expertise to bring specialized solutions to customers across the healthcare ecosystem.

SOLUTIONS

NeuroBlu Solutions

NeuroBlu platform seamlessly connects our behavioral health data and analytics capabilities with our behavioral health expertise to bring specialized solutions to customers across the healthcare ecosystem.

Reimagining Behavioral Health supporting graphic
Reimagining Behavioral Health supporting graphic

NeuroBlu is a behavioral health real-world data and analytics solution that enables users to access the industry-leading proprietary behavioral health dataset with structured outcome measures and seamless AI-powered analytic tools.

NeuroBlu’s robust tools drives real-world evidence generation with unparalleled ease, providing bespoke research and support services to solve complex behavioral health questions.

Learn More

Reimagining Behavioral Health supporting graphic

NeuroBlu Health is a behavioral health care management and analytics solution that leverages NeuroBlu’s robust database to provide clinicians with valuable data-driven recommendations, assisting clinicians in making patient-specific care decisions in behavioral health.

NeuroBlu Health is equipped with user-friendly tools that streamline care management processes, freeing up clinicians to devote their time and resources to patients.

Learn More

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More solutions coming soon.

Support

We're Here to Help

We know data is only as useful as its impact. Our team has spent years building expertise in the intricacies of behavioral health data, and we will work collaboratively with you to help generate evidence that matters.

Training and Reference Tools

Rapid onboarding and training with dedicated customer support plus in-depth tutorials and FAQs.

Customer Success

Dedicated support to help you extract the most value from your NeuroBlu license.

Advanced Analytics Services

Tap into our data science and machine learning expertise for custom analytics.

LATEST ANNOUNCEMENTS

Publication

Psych Congress 2022: Holmusk Presents Two Posters on Behavioral Health Real-world Evidence

September 18, 2022

VIEW

New Release

Gain better insights with 1M+ patient lives data and break silos by sharing projects

September 15, 2022

VIEW

New Release

Accelerate drug impact comparison and easily switch datasets

September 1, 2022

VIEW
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LATEST ANNOUNCEMENTS
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Over 300 psychiatry-specific labels

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NLP model trained on notes from over 11,000 clinicians and 6 million data points

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Disease severity score for every encounter

VIEW ALL

New Release

PRO

September 15, 2022

General

August 11, 2022

Publication

September 18, 2022

Event

August 21, 2021

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