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NeuroBlu Data is the largest source of real-world behavioral and mental health data - longitudinal and NLP enriched to unlock clinical insights.

Leading Source for
Behavioral & Mental Health
Real-World Data
36,500,000+

Patients

40+

Geographically-diverse health systems

20+

Years of longitudinal data

Linkability

Connects patient data across time and care settings to enable longitudinal analysis and richer clinical insights.

Longitudinal

Over 20 years of behavioral health data from diverse care environments including inpatient, outpatient, emergency, crisis, and community settings.

Comprehensive

Combines structured data with NLP-enriched clinical notes to support multidimensional cohort development and outcomes research.

Depth

Offers validated behavioral health variables—assessments, symptoms, testing, and interventions—for advanced analytics and decision-making.

Our data encompasses over 36 million patients across more than 20 years treated in multiple care settings - inpatient, outpatient, and primary care. Structured fields in NeuroBlu Data include:

Behavioral health conditions

  • Major depressive disorder

9.7M+ patients

  • Substance use disorder

8.9M+ patients

  • Generalized anxiety disorder

4.4M+ patients

  • Attention deficit hyperactivity disorder

3.7M+ patients

  • Post-traumatic stress disorder

1.6M+ patients

  • Schizophrenia

442K+ patients

  • Bipolar I disorder

439K+ patients

  • Schizoaffective disorder

349K+ patients

  • Obsessive compulsive disorder

349K+ patients

  • Bipolar II disorder

299K+ patients

  • Borderline personality disorder

182K+ patients

    Behavioral health assessments

    • Brief Bipolar Disorder Symptom Scale (BDSS)
    • Brief Negative Symptom Assessment (BNSA)
    • Clinical Global Impressions (CGI-I/CGI-S)
    • Columbia-Suicide Severity Rating Scale (C-SSRS)
    • Global Assessment of Functioning (GAF)
    • Patient Health Questionnaire-9/2 (PHQ-9/2)
    • Positive Symptom Rating Scale (PSRS)
    • The Daily Living Activities–20 (DLA-20)

    • The Quick Inventory of Depressive Symptomatology (QIDS)

    and more

    Pharmacological treatments

    • Antidepressants

    • Antipsychotics

    • Anxiolytics
    • Dementia treatments

    • Hypnotics and sedatives

    • Mood stabilizers
    • Psycholeptics
    • Psychostimulants

    and more

    Cognitive assessments

    • Quick Screening for Early Dementia Detection (Mini-Cog©)
    • Mini Mental Status Examination (MMSE®)
    • Montreal Cognitive Assessment (MoCA)

    and more

    NeuroBlu NLP

    In addition, NeuroBlu Data is enriched through novel natural language processing (NLP) techniques that extract deep clinical context from free-text within the EHR—making the data more actionable for research than ever before.

    Key enriched data elements include:

    Behavioral Observations & Symptoms

    Extracts rich clinical detail from free-text notes, including mood, cognition, behavior, and affect—capturing nuanced symptoms that structured fields often miss (e.g., anhedonia in major depressive disorder).

    Clinical Outcomes & Psychosocial Context

    Monitors patient progress—improvement, deterioration, or stability—over time, while incorporating psychosocial dimensions that influence behavioral health outcomes.

    Real-World Safety & 
Treatment Signals

    Leverages unstructured clinical narratives to surface real-world side effects, adverse events, and therapeutic responses, offering a valuable lens for drug safety surveillance, comparative effectiveness studies, and optimization of treatment strategies.

    Learn more through our peer-reviewed publications exploring our novel NLP methodologies and their impact on improving clinical practice.

    NeuroBlu Data supports diverse needs

    Research and Development

    Support clinical development and increase success of clinical trials.

    R&D Strategy

    • Identify patient subpopulations with unmet needs, such as opioid use disorder patient with poor outcomes despite being on a treatment regimen.

    Clinical Development

    • Significantly accelerate clinical trial recruitment by screening patient characteristics efficiently. For instance, easily identify characteristics of patients with Major Depressive Disorder who exhibit symptoms of anhedonia.
    • Understand characteristics associated with varying levels of severity in patients with Major Depressive Disorder, in order to create patient subsegments to inform trial design for compounds targeting treatment-resistant depression.

    Medical Affairs

    Derive patient specific insights and population level trends in behavioral health using AI/ML algorithms on large sets of real-world behavioral health data.

    • Compare key endpoints — such as Clinical Global Impression-Severity (CGI-S), Global Assessment of Function (GAF), and side effect burden — for patients on competitor drugs to provide evidence of differentiated benefit.
    • Assess patient-centric outcomes — such as mood, function, and engagement — that can significantly impact outcomes in real-world settings, including treatment adherence, clinician prescription decisions, and overall patient health.
    • Evaluate prescription patterns of off-label use of drugs for Major Depressive Disorder to identify related behavioral health conditions for further clinical evaluation.
    • Guide evidence-driven care to enhance care management for patients at risk and to improve behavioral health outcomes.
    • Produce publications demonstrating therapeutic benefit in real-world settings to increase visibility and influence among key opinion leaders and healthcare professionals.

    Market Access and HEOR

    Evaluate comparative effectiveness of pharmacological treatments in the real world and support value-based care.

    • Establish cost-benefit by determining comparative effectiveness of treatments beyond standard clinical endpoints, such as hospitalization among patients on different drug formulations (e.g. oral versus long-acting injectable atypical antipsychotics).
    • Measure drug performance in real-world settings and identify opportunities for value-based strategies.
    ANALYTICS Software

    Access insights in just a few clicks

    Quickly analyze and gain immediate insight from millions of de-identified electronic health records with NeuroBlu Analytics, a powerful data analytics software.

    To improve and optimize patient outcomes, we first need a deep understanding of how care is delivered. Powered by Holmusk's best-in-class behavioral health database, NeuroBlu Analytics organizes and makes available the most important resource to support this understanding—clinical data captured during care delivery.

    See Neuroblu Analytics in Action

    Care management Software

    NeuroBlu Health is a behavioral health-focused care management and population health solution that unlocks real-world, structured data from providers’ electronic health records (EHRs) to deliver fast, precise, and actionable insights.

    Reduce Avoidable Costs of Care

    Leverage behavioral health-specific risk detection and patient complexity insights to identify potential crises early, enabling timely intervention that reduces readmissions and saves costs.

    Improve Care Operations

    Optimize workload, streamline care coordination, and reduce administrative burdens — freeing up clinical capacity, supporting provider well-being, and boosting overall system efficiency.

    Advance Quality of Care

    Use automated insights to ensure adherence to clinical protocols, close care gaps, monitor outcomes, and drive quality improvement.

    Customized Support

    Conduct analyses alongside our team of clinical and data science experts, who can provide support tailored to your needs.

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